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Dr. Amalfi appears in the Top 100 

Innovators & Entrepreneurs Magazine

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Dr. Raffaele Luca Amalfi


Dr. Raffaele Luca Amalfi is the CEO, co-founder, and chairman of SEGUENTE Inc., an information and communications technology (ICT) company that offers end-to-end liquid-cooled hardware platforms with integrated Artificial Intelligence (AI) software solutions for data center and telecom market segments. An innovator, visionary, and industry influencer, he has received recognition globally for his accomplishments and groundbreaking technological innovations. His efforts have significantly impacted the industry and the broad thermal community; notably, by his many discoveries and collaborating with industry leaders from IBM, Nokia, Alcatel-Lucent, Qualcomm, and others. “To be a successful leader, you need to know the business, the market, the value proposition, and most importantly, you must  understand your customers’ needs and requirements,” he stated. These areas define the unique intersection in which Dr. Amalfi thrives as the driving force of SEGUENTE’ strategic business, technology, product roadmaps, capital objectives, and growth goals.


At SEGUENTE, Dr. Amalfi leads a team of industry experts that provide revolutionary seamlessly integrated cooling solutions for high-performance servers and racks. Together, they have developed a direct-to-chip two-phase liquid cooling product, ColdWare™, that incorporates advanced AI software for monitoring and optimization. “We are building a company that maximizes opportunities and delivers flexible solutions for our customers, as we invest in new product development that aligns with our core technology roadmap and business goals,” he said. In addition, Dr. Amalfi is passionate about cultivating strategic relationships with industry partners to accelerate SEGUENTE’s holistic end-to-end systems that deliver performance, efficiency, and sustainability to the ICT industry.


Headquartered in Melbourne, Florida (USA), SEGUENTE has AI, pragmatic modeling, computational fluid dynamics, engineering design, assembly, and test capabilities, along with R&D. SEGUENTE addresses the digital transformation demands by offering innovative products and services that enable customers to achieve sustainability goals and enhanced performance. SEGUENTE’s hardware solutions include advantages such as higher compute, flexibility, reliability, a significant reduction in power usage and total cost of ownership, a waterless implementation with ultra-low GWP working fluids, and it is easy to deploy in existing and new infrastructures. In addition, SEGUENTE has built the ecosystem of key partners and aligned the industry supply chain for business scaling and deploying turn-key systems.


Dr. Amalfi has a doctoral degree in mechanical engineering, a master’s in energy engineering, and a bachelor’s in mechanical engineering. He held strategic roles in several corporate companies. He was a principal innovator at Nokia Bell Labs USA, where he led R&D and business activities in thermal management of high-performance communication systems; and as a scientific collaborator and laboratory operations manager at the Swiss Federal Institute of Technology of Lausanne (EPFL) in Switzerland, where he made outstanding contribution in the field of two-phase liquid cooling for complex systems. Other past positions include researcher at Alcatel-Lucent USA, where he investigated the benefits of liquid cooling technologies for network equipment; and mechanical engineer at IBM Research Laboratory in Switzerland, where he developed a novel cooling system for high-performance processors.


Dr. Amalfi has authored over 20 patents in advanced thermal management solutions for the ICT industry and over 60 scientific publications in leading journals, conference proceedings, and handbooks. He is part of the leadership committees for IEEE and ASME thermal conferences, a member of the ASME K-16 Heat Transfer Committee and the OCP Heat Reuse Steering Committee, a guest editor for the ASME Journal of Electronic Packaging, and the recipient of numerous industry and government awards for groundbreaking innovations, including this year’s Internet 2.0 Outstanding Leadership Award. Other awards include the Bell Labs Outstanding Inventor Award; EPFL Outstanding Researcher Award; Alcatel-Lucent International Ph.D. Award; and Top Academic Achiever Award for two consecutive years, Federico II University, Naples, Italy.



Dr. Raffaele Luca Amalfi

CEO, Co-Founder, Chairman of the Board — SEGUENTE Inc.


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